Publicaciones

  • Cerda Catalina, Yáñez Javiera, Seguel Enrique,  Guinez-Molinos S. (2022). “Rendimiento de EuroSCORE II en Latinoamérica: una revisión sistemática” Revista Médica de Chile, In press.
  • Forero, O., Guzmán, Jiménez-Aspee, F., Echeverría, J., Wehinger, S., Valenzuela, C., Araya-Maturana, R., Martínez-Cifuentes, M. (2022). An In Vitro and In Silico Study of Antioxidant Properties of Curcuminoid N-alkylpyridinium Salts: Initial Assessment of Their Antitumoral Properties, Antioxidants,11(6).
  • Sergio Guinez-Molinos, Benjamín Castillo, Gomar Sancho C (2022). Medical student’s perceptions of online learning during COVID-19 pandemic in Chile. International Journal of Medical Education. In press.
  • Sergio Guinez-Molinos, Benjamín Castillo, Paulina Espinoza (2022). Caracterización de la simulación clínica en Chile durante la pandemia COVID-19. Revista Médica de Chile. In Press
  • Sergio Guinez-Molinos, Jaime González Díaz, Carol Barahona Ponce and Justo Lorenzo Bermejo (2022). Development of an application for electronic retrieval of patient and sample information in Latin American regions with a high incidence of gallbladder cancer. Pers. Med. In press.
  • Huilcaman, R., Venturini W., Fuenzalida, L., Cayo, A., Segovia, R., Valenzuela, C., Moore-Carrasco, R., Brown, N. (2022). Paltelets, a Key Cell in Inflammation and Atherosclerosis Progression, Cells, 11(6).
  • Mazola, Y., Márquez Montesinos, JCE., Ramírez, D., Zúñiga, L., Decher, N., Ravens, U., Yarov-Yarovoy, V., González, W. (2022). COMMON STRUCTURAL PATTERN FOR FLECAINIDE BINDING IN ATRIAL-SELECTIVE KV1.5 AND NAV1.5 CHANNELS: A COMPUTATIONAL APPROACH, Pharmaceutics, 14(7). doi: 10.3390/pharmaceutics14071356.
  • Joviano-Santos, JV., Valadão, PAC., Magalhães-Gomes, MPS., Fernandes, LF., Diniz, DM., Machado, TCG., Soares, KB., Ladeira, MS., Massensini, AR., Gomez, MV., Miranda, AS., Tápia, JC., Guatimosim, C. (2022). Neuroprotective effect of CTK 01512-2 recombinant toxin at the spinal cord in a model of Huntington’s disease, Exp Physiol, 107(8),933-945.
  • Riveros, A., Vega, C., Negroni, M., Villagrán, F., Binvignat, O., Olave, E. (2022).Variations   of   the   Cerebral   Arterial   Circle. Morphological   and   Clinical   Analysis. Int. J. Morphol.40(3),632-639.
  • Solís Anez, E., Salles, P., Rojas, N., Benavides, O., Chaná Cuevas, P. (2022),,Neuroepidemiology
  • Veronica Vitriol, Alfredo Cancino, Andres Sciolla, Sergio Guinez-Molinos , Jorge Calvo, Marcela Ormazabal, Johanna Kreither, Soledad Ballesteros, Maria De La Luz Aylwin (2022). Effect of a collaborative multidimensional approach versus usual care on the resolution of adult depression in primary care in Chile: study protocol for a single blinded cluster randomized controlled trial. F1000Research, 11:203.
  • Zúñiga, L., Cayo, A., González, W., Vilos, C., Zúñiga, R.(2022). POTASSIUM CHANNELS AS A TARGET FOR CANCER THERAPY: CURRENT PERSPECTIVES,Onco Targets, 20(15),783-797. doi: 10.2147/OTT.S326614.

  • Zúñiga, R., Mancilla, D., Rojas, T., Vergara, F., González, W., Catalán, MA., Zúñiga, L. (2022). A DIRECT INTERACTION BETWEEN CYCLODEXTRINS AND TASK CHANNELS DECREASES THE LEAK CURRENT IN CEREBELLAR GRANULE NEURONS. Biology (Basel),11(8). doi:10.3390/biology11081097

  • Binvignat, O.,Losardo, R.(2021).El Dr. Nicolás Triantafilo Klotza, los inicios de la Universidad de Antofagasta y la inmigración griega en el norte de Chile. health. med. Sci.
  • Cayo, A., Segovia, R., Venturini, W., Moore-Carrasco, R., Valenzuela, C., Brown, N. (2021). mTOR Activity and Autophagy in Senescent Cells, a Complex Partnership, International Journal of Molecular Sciences,22(15).
  • Guinez-Molinos S., Gomar Sancho C. (2021). “Collaborative clinical simulation in cardiologic emergency scenarios for medical students. An exploratory study on model applicability and assessment instruments”. GMS J Med Educ 2021;38(4):Doc76. DOI:https://dx.doi.org/10.3205/zma001472
  • Guinez-Molinos S, Gonzalez Díaz J, Gomar Sancho C, Espinoza P, Constenla G. A Web Platform (MOSAICO) to Design, Perform, and Assess Collaborative Clinical Scenarios for Medical Students: Viewpoint. JMIR Med Educ 2021;7(1):e23370. URL:https://mededu.jmir.org/2021/1/e23370. DOI: 10.2196/23370.
  • Guinez-Molinos S, Andrade JM, Medina Negrete A, Espinoza Vidal S, Rios E. Interoperable Platform to Report Polymerase Chain Reaction SARS-CoV-2 Tests from Laboratories to the Chilean Government: Development and Implementation Study. JMIR Med Inform. 2021 Jan 20;9(1):e25149. doi: 10.2196/25149. PMID: 33417587.
  • Hernández-Olivos, R., Muñoz, M., Núñez, E., Camargo-Ayala, P. A., Garcia-Huidobro, J., Pereira, A., Nachtigall, F. M., Santos, L. S., & Rivera, C. (2021). Salivary proteome of aphthous stomatitis reveals the participation of vitamin metabolism, nutrients, and bacteria. Scientific reports, 11(1), 15646. https://doi.org/10.1038/s41598-021-95228-8

  • Huilcaman, R., Olate, A., Venturini, W., Treuer, A., Valenzuela, C., Brown, N., Moore-Carrasco, R .(2021).Endothelial transmigration of platelets depends on soluble factors released by activated endothelial cells and monocytes, Platelets 32(8)

  • Losardo, R.J., Binvignat, O.(2021).Simbología Gráfica Anatómica en el Proceso de Comunicación. International Journal of Morphology,
  • Meirovitch, Y., Kang, K., Draft, R. W., Pavarino, E. C., Fernanda, M., Echeverri, H., Yang, F., Turney, S. G., Berger, D. R., Peleg, A., Schalek, R. L., Lu, J., Livet, J., Tapia, J.-C., & Lichtman, J. W. (2021). Neuromuscular connectomes across development reveal synaptic ordering rules. BioRxiv, 2021.09.20.460480. https://doi.org/10.1101/2021.09.20.460480
  • Rodríguez-Herrera, R., Gamboa Monge, G.,  Losardo, R., Binvignat, O. (2021).Irrigación renal múltiple . Revista Argentina de Anatomía.
  • Rodríguez-Herrera, R., Binvignat, O., Losardo, R. (2021).Términos anatómicos populares en costa rica. Diversidad que genera imprecisión en la terminología médica.  Crea Ciencia, 14(1).

  • Valdebenito-Maturana, B., Guatimosim, C., Carrasco, MA., Tapia, JC. (2021). Spatially Resolved Expression of Transposable Elements in Disease and Somatic Tissue with SpatialTE, Int J Mol Sci, 22(24)

  • Valdebenito-Maturana, B., Torres, F., Carrasco, M., Tapia, JC. (2021). Differential regulation of transposable elements (TEs) during the murine submandibular gland development, Mobile DNA, 12(23). https://doi.org/10.1186/s13100-021-00251-1.

  • Valdebenito-Maturana, B., Arancibia, E., Riadi, G., Tapia, JC., Carrasco, M. (2021). Locus-specific analysis of Transposable Elements during the progression of ALS in the SOD1G93A mouse model, PLoS One, 16(10). https://doi.org/10.1371/journal.pone.0258291

  • Valdés, F., Arévalo, B., Gutiérrez, M., García-Castillo, V., Salgado-García, R., Pérez-Plasencia, C, Valenzuela, C, Cayo, A, Olate-Briones, A., Brown, N.(2021), Two new adenosine derivatives and their antiproliferative properties, an in-vitro evaluation, Anti-Cancer Agents in Medical Chemistry 21(7).

  • Vitriol, V., Cancino, A., Serrano, C., Ballesteros, S., Ormazábal, M., Leiva-Bianchi, M.,  Salgado, C., Cáceres,C., Potthoff, S., Orellana, F., Asenjo, A. (2021). Latent Class Analysis in Depression, Including Clinical and Functional Variables: Evidence of a Complex Depressive Subtype in Primary Care in Chile, Depression Research and Treatment. https://doi.org/10.1155/2021/6629403
  • Binvignat, O., Olloquequi, J. (2020).Excitotoxicity as a Target Against Neurodegenerative Processes. (2020). Current Pharmaceutical Design,26(12),1251-1262.

  • Bustos, D., Bedoya, M., Ramírez, D., Concha, G.,Zúñiga, L ., Decher, N., Hernández, E.W.,Sepúlveda, F.V., Martínez, L., González, W. (2020). ELUCIDATING THE STRUCTURAL BASIS OF THE INTRACELLULAR PH SENSING MECHANISM OF TASK-2 K2P CHANNEL, Int. J. Mol. Sci,21(2). doi: 10.3390/ijms21020532

  • Klein, F., Cáceres, D., Carrasco, MA., Tapia, JC., Caballero, J., Alzate-Morales, J., Pantano, S.J. (2020). Coarse-Grained Parameters for Divalent Cations within the SIRAH Force Field,Journal of Chemical Information and Modeling, 60(18), 3935-3943. DOI: 10.1021/acs.jcim.0c00160.
  • Venturini, W., Olate, A.,Valenzuela, C., Méndez, D., Fuentes, E., Cayo, A., Mancilla, D., Brown, N., Moore-Carrasco, R. (2020), Platelet Activation Is Triggered by Factors Secreted by Senescent Endothelial HMEC-1 Cells In Vitro, International Journal of Molecular Sciences, 21(9).
  • Zúñiga, R., Concha, G., Cayo, A., Cikutović-Molina, R., Arevalo,B., González, W., Catalán, MA., Zúñiga, L. (2020). WITHAFERIN A SUPPRESSES BREAST CANCER CELL PROLIFERATION BY INHIBITION OF THE TWO-PORE DOMAIN POTASSIUM (K2P9) CHANNEL TASK-3. Biomed Pharmacother. doi: 10.1016/j.biopha.2020.110383.
  • Cárdenas-Valenzuela, J., Binvignat-Gutiérrez, O.(2019).Glosario anatómico etnográfico Rapa Nui. International Journal of Morphology, 37(1), 258–264.
  • Cikutovi ́c-Molina, R., Herrada, A. A, González, W., Brown, N., Zúñiga, L. (2019). TASK-3 GENE IN KATO III AND MKN-45 HUMAN GASTRIC ADENOCARCINOMA CELL LINES. J. Mol. Sci.doi: 10.3390/ijms20236077.
  • Losardo, R.,Binvignat, O., Pando-Miranda, J.R. (2019). Bernardino Ramazzini: un pionero de la medicina del trabajo. . Revista De La Asociación Médica Argentina, 19(4), 28-33.
  • Martínez, F, Cifuentes, M, Tapia, JC, Nualart, F. J. (2019). The median eminence as the hypothalamic area involved in rapid transfer of glucose to the brain: functional and cellular mechanisms, Mol Med, 97(8),1085-109
  • Pérez, V., Bermedo-Garcia, F., Zelada, D., Court,FA., Pérez,MA., Fuenzalida, M., Ábrigo, J, Cabello-Verrugio, C., Moya-Alvarado, G., Tapia, JC., Valenzuela, V., Hetz,C., Bronfman, FC., Henríquez, JP. (2019).The p75 NTR neurotrophin receptor is required to organize the mature neuromuscular synapse by regulating synaptic vesicle availability, acta neuropathol commun, 7(147). https://doi.org/10.1186/s40478-019-0802-7
  • Ramírez, D., Concha, G., Arévalo, B., Prent-Peñaloza, L., Zúñiga, L., Kiper, AK., Rinné, S., Reyes-Parada, M., Decher, N., González, W., Caballero, J. (2019) . DISCOVERY OF NOVEL TASK-3 CHANNEL BLOCKERS USING A PHARMACOPHORE-BASED VIRTUAL SCREENING. J. Mol. Sci. doi: 10.3390/ijms20164014.
  • Rodríguez-Herrera, R., Losardo, R.J., Binvignat, O.(2019).La anatomía humana como disciplina indispensable en la seguridad de los pacientes. International Journal of Morphology, 37(1), 241-250.
  • Valadão, PAC, de Aragã, BC., Andrade, JN., Magalhães-Gomes, MPS., Foureaux, G., Joviano-Santos, JV., Nogueira, JC., Machado, TCG., de Jesus, ICG., Nogueira, JM., de Paula, RS., Peixoto, L., Ribeiro, FM., Tapia, JC., Jorge, ÉC., Guatimosim, S., Guatimosim, C. (2019). Abnormalities in the Motor Unit of a Fast-Twitch Lower Limb Skeletal Muscle in Huntington’s Disease, ASN Neuro.https://doi.org/10.1177/1759091419886212
  • Valenzuela, C., Quintanilla, R., Olate, A., Cayo, A., Mancilla, D., Moore-Carrasco, R., Brown, N. (2019), SASP-Dependent Interactions between Senescent Cells and Platelets Modulate Migration and Invasion of Cancer Cells, International Journal of Molecular Sciences20(21).
  • Brown, Nelson (2018). D-Type cyclins and cancer. Editorial Springer-Nature (Editor).
  • Brown, Nelson (2018). Semi-synthesis, characterization and evaluation of new adenosine derivatives. Molecules Journal (coautor).
  • Brown, Nelson (2018).Adenosine: synthetic methods of its derivatives and antitumor activity. Mini-reviews in Medicinal Chemistry (coautor).
  • Brown, Nelson; Valenzuela, Claudio (2018). Cyclin D1, metabolism and the autophagy-senescence balance. Capítulo de libro.
  • Brown, Nelson; Zúñiga, Leandro; Valenzuela, Claudio (2018). TASK-3 downregulation triggers cellular senescence and growth inhibition in breast cancer cell lines. International Journal of Molecular Sciences.
  • Cancino, A., Leiva-Bianchi,M., Serrano,C., Ballesteros-Teuber, S., Cáceres,C., Vitriol, V., (2018).Factors Associated with Psychiatric Comorbidity in Depression Patients in Primary Health Care in Chile, Depression Research and Treatment.https://doi.org/10.1155/2018/1701978
  • Chan, H.L., Beckedorff, F., Zhang, Y., Garcia-Huidobro, Jenaro, Jiang, H., Colaprico A., Bilbao, D., Figueroa, M.E, LaCava, J., Shiekhattar, R., Morey, L.(2018) . Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms. Nat Commun 9, 3377 . https://doi.org/10.1038/s41467-018-05728-x
  • Concha, G., Bustos, D., Zúñiga, R., Catalán, MA., Zúñiga, L. (2018) THE INSENSITIVITY OF TASK-3 K2P CHANNELS TO EXTERNAL TETRAETHYLAMMONIUM (TEA) PARTIALLY DEPENDS ON THE CAP STRUCTURE, Int J Mol Sci, 19(8). doi: 10.3390/ijms19082437.
  • Guinez-Molinos S., Carmen Gomar Sancho, Patricio Maragaño Lizama (2018). Simulación clínica colaborativa en estudiantes de medicina de Chile y España. Revista Médica de Chile, 146 (5).
  • Hirabayashi, Y, Tapia, JC, Polleux, F. (2018). Correlated Light-Serial Scanning Electron Microscopy (CoLSSEM) for ultrastructural visualization of single neurons in vivo, Rep, 8(1). https://doi.org/10.1038/s41598-018-32820-5.

  • Moscol González, J. (2018) El conocimiento anatómico en el Perú preincaico. Revista de la Asociación Médica Argentina, 131(4).

  • Núñez-Cook, S., Gajardo, P., Lizana, P.A, Vega-Fernadez,G., Hormazabal-Peralta,A., Bingvinat, O. (2018). Percepción de los Estudiantes de Anatomía Humana Frente a un Método de Enseñanza y Aprendizaje Basado en la Construcción de un Modelo de Pelvis. (2018). J. Morphol,36(1),221-225.
  • Olloquequi, J., Cornejo-Córdova, E., Verdaguer, E., Soriano, F.X., Binvignat, O., Auladell, C., Camins, A. (2018). Excitotoxicity in the pathogenesis of neurological and psychiatric disorders: Therapeutic implications,Journal of Psychopharmacology,32(2), 265-275.
  • Pino-Ramírez. G., Solís-Añez, E. (2018). Percepción de enfermedad en personas con Trastornos hereditarios del tejido conectivo. Orbis Revista científica Ciencias Humanas,39,44-61
  • Ramírez, D., Zúñiga, R., Concha, G., Zúñiga, L. (2018) HCN CHANNELS: NEW THERAPEUTIC TARGETS FOR PAIN TREATMENT, Molecules, 23(9). doi:10.3390/molecules23092094.
  • Vitriol V, Cancino A, Serrano C, Ballesteros S, Potthoff S. (2018). Remission in Depression and Associated Factors at Different Assessment Times in Primary Care in Chile, Clinical Practice & Epidemiology In Mental Health, 14, 78–88. https://doi.org/10.2174/1745017901814010078
  • Guinez-Molinos, Sergio (2017). Chile’s National Center for Health Information Systems: A Public-Private Partnership to Foster Health Care Information Interoperability. Stud Health Technol Inform.
  • Brown, Nelson; Valenzuela, Claudio (2017). The potential role of senescence as a modulator of platelets and tumorigenesis. Frontiers in Oncology. International Journal of Molecular Sciences.
  • Brown, Nelson; Valenzuela, Claudio (2017). Palbociclib-induced autophagy and senescence in gastric cancer cells. Experimental Cell Research.
  • Zúñiga, Jessica (2017).The Role of Propolis in Oxidative Stress and Lipid Metabolism: A Randomized Controlled Trial. Evidence-based Complementary and Alternative Medicine.
  • Vitriol, Verónica (2017). Depresión adulta y experiencias infantiles adversas: evidencia de un subtipo depresivo complejo en consultantes de la atención primaria en Chile. Revista medica de Chile.
  • Vitriol, Verónica (2017). Depresión y trauma temprano: hacia una caracterización clínica de perfiles de consulta en un servicio de salud secundario. Revista chilena de neuro-psiquiatría.
  • Vitriol, Verónica (2017). Factors Associated With Greater Severity of Depression in Chilean Primary Care Patients. Prim Care Companion CNS Disord.
  • Brown, Nelson; Zúñiga, Leandro; Valenzuela, Claudio (2016). Expression and cellular localization of HCN channels in rat cerebellar granule neurons. Biochemical and biophysical research communications.
  • Brown, Nelson (2016). CDK6 kinase activity is required for initiation of Notch-mediated T-cell acute lymphoblastic leukemia formation. Leukemia Journal (coautor).
  • Zúñiga, Leandro (2016). Understanding the CAP structure in K2P channels. Front Physiol (coautor).
  • Zúñiga, Leandro (2016). Cardiovascular action of insulin in health and disease: Endothelial L-Arginine transport and cardiac voltage-dependent potassium channels. Front Physiol (coautor).
  • Mariqueo, Trinidad (2016). Functional modulation of glycine receptors by the alkaloid gelsemine. Br J Pharmacol (coautor).
  • Trujillo, Gonzalo (2016). Pulpa Dentaria Sana vs. Pulpitis Reversible: Caracterización Estereológica de Fibroblastos. International Journal of Morphology.
  • Trujillo, Gonzalo (2016). Healthy Normal Dental Pulp vs. Reversible Pulpitis: Stereological Characterization of Fibroblasts. International Journal of Morphology.
  • Vitriol, Verónica (2016). Childhood trauma and psychiatric comorbidities in patients with depressive disorder in primary care in Chile. Journal of Trauma & Dissociation.
  • Guinez-Molinos, Sergio; Maragaño, Patricio (2016). A collaborative clinical simulation model for the development of competencies by medical students. Medical Teacher.
  • García-Huidobro, Jenaro (2016). Sustained zero-order delivery of GC-1 from a nanochannel membrane device alleviates metabolic syndrome. International Journal of Obesity (coautor).
  • Solis, Ernesto (2016). Identificación de la mutación ∆f508 en afectados con íleo meconial. Revist Obstet Ginecol Venez (coautor).
  • Solis, Ernesto (2016). Síndrome de PAGOD y anomalías vasculares ¿es un defecto de la angiogénesis embrionaria?un nuevo caso y revisión. Invest Clin (coautor).
  • Solis, Ernesto (2016). Valores de referencia de β-Glucosidasa y quitotriosidasa en gotas de sangre seca en lactantes venezolanos. Arch Ven Puer pediatr (coautor).
  • Solis, Ernesto (2016). Percepción de enfermedad en personas con Trastornos hereditarios del tejido conectivo. Orbis Revista científica Ciencias Humanas (coautor).
  • Brown, Nelson (2015).BRCA1-haploinsufficency induces premature senescence, rapid telomere erosion and genomic instability in a cell and tissue specific manner. Nature Communications (coautor).
  • Mariqueo, Trinidad (2015). Evidence for α-helices in the large intracellular domain mediating modulation of the α1-glycine receptor by ethanol and Gβγ. J Pharmacol Exp Ther (coautor).
  • Mariqueo, Trinidad (2015). Advances in the pharmacology of lGICs auxiliary subunits. Pharmacol Res.
  • Aylwin, María de la Luz (2015). Odorant recognition using biological responses recorded in olfactory bulb of rats. Comput Biol Med.
  • Aylwin, María de la Luz (2015). The Alteration of Neonatal Raphe Neurons by Prenatal-Perinatal Nicotine. Meaning for Sudden Infant Death Syndrome. Am J Respir Cell Mol Biol.
  • Zúñiga, Jessica (2015). Chilean Strawberry Consumption Protects against LPS-Induced Liver Injury by Anti-Inflammatory and Antioxidant Capability in Sprague-Dawley Rats. Evidence-based Complementary and Alternative Medicine.
  • Solis, Ernesto (2015). Polimorfismo C677T del gen de la metilentetrahidrofolato reductasa en madres de niños afectados con defectos del tubo neural. Invest Clin (coautor).
  • Brown, Nelson (2014). Tumor Suppressor Genes. Capítulo de libro.
  • Brown, Nelson (2014).The selective cytotoxicity elicited by phytochemical extract from Senecio graveolens (Asteraceae) on breast cancer cells is enhanced by hypoxia. International Journal of Oncology (coautor).
  • Zúñiga, Leandro (2014). Differential expression of two-pore domain potassium channels in rat cerebellar granule neurons. BBRC.
  • Mariqueo, Trinidad (2014). Altered sedative effects of ethanol in mice with α1 glycine receptor subunits that are insensitive to Gβγ modulation. Neuropsychopharmacology (coautor).
  • Mariqueo, Trinidad (2014). Effects of ethanol on glycinergic synaptic currents in mouse spinal cord neurons. J Neurophysiol.
  • Vitriol, Verónica (2014). Response of primary care teams to manage mental health problems after the 2010 earthquake. Revista medica de Chile.
  • Vitriol, Verónica (2014). Depression and Psychological Trauma: An Overview Integrating Current Research and Specific Evidence of Studies in the Treatment of Depression in Public Mental Health Services in Chile. Depression research and treatment.
  • Guinez-Molinos, Sergio (2012). The Reputation-Based Trust Model for AliEn2. Computing in High Energy and Nuclear Physics (CHEP) (Académico conferenciante).
  • Guinez-Molinos, Sergio (2012). Study of interaction energies between the PAMAM dendrimer and nonsteroidal anti-inflammatory drug using a distributed computational strategy and experimental analysis by ESI-MS/MS (2012) – The Journal of Physical Chemistry B (coautor).
  • Guinez-Molinos, Sergio (2012). Aplicación de computación de alto rendimiento y sistemas distribuidos en análisis de datos biológicos. (2012) – Tecnologías NBIC en Salud, El papel protagonista de la Nanociencia. Ciencia y Tecnología para el Desarrollo CYTED (coautor).
  • Guinez-Molinos, Sergio (2011). Nanoinformatics: an emerging area of information technology at the intersection of bioinformatics, computational chemistry and nanobiotechnology (2011) – Biological research (coautor).